High risk Human Papilloma Virus infection in teenagers right
after the start of sexual activity
T. Major and Z. Krasznai
University of Debrecen,
Medical Health and Science Centre, Department of Obstetrics and Gynecology,
Introduction It is well known that high-risk Human Papilloma
Virus (high-risk HPV) infection can be detected at a relatively high percentage
in sexually active teenagers. No large studies were carried out in
Central-European countries before, and the previous studies did not count with
the time elapsed from the start of sexual activity. In our study we wanted to
determine the prevalence of the infection in teenagers right after the start of
sexual activity, and determine its correlation with other factors, such as age,
time passed from the start of sexual activity, contraception method used,
smoking, cytologic or kolposcopic abnormality.
Materials and methods The study
population were 97 asymptomatic female patients (age 14-19), 1 week to 6 months
after the first sexual intercourse.
Results and conclusions We have found a
relatively high prevalence (33%) of high-risk HPV infection in teenagers right
after the start of their sexual lives. This percentage of infection is not rare
due to the relating literature, but previously no larger studies were carried
out in Central-Europe, and it is a new and interesting fact, that the high-risk
HPV positivity reaches this high prevalence in a very short time after the start
of sexual activity, and does not show correlation with the time passed since the
first intercourse. In our work we also searched for the correlation of infection
with cytologic abnormality, kolposcopic atypia, condom use and smoking. We found
the strongest correlation of the infection with colposcopic atypia. The
correlation with smoking and cytologic atypia was not significant, which can be
due to the lack of time for these factors from the start of the infection.
Condom use decreased the infection rate, although was not protective against it.